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1

AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms

Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu

Journal:

Year:

2016

Language:

english

File:

PDF, 760 KB

english, 2016

2

Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape

Salminen, Antero, Haapasalo, Annakaisa, Kauppinen, Anu, Kaarniranta, Kai, Soininen, Hilkka, Hiltunen, Mikko

Journal:

Progress in Neurobiology

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

3

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Antero Salminen, Anu Kauppinen, Kai Kaarniranta

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

4

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

Antero Salminen, Johanna Ojala, Kai Kaarniranta…

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 347 KB

english, 2012

5

Inflammation and its role in age-related macular degeneration

Kauppinen, Anu, Paterno, Jussi J., Blasiak, Janusz, Salminen, Antero, Kaarniranta, Kai

Journal:

Cellular and Molecular Life Sciences

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

6

Control of p53 and NF-κB signaling by WIP1 and MIF: Role in cellular senescence and organismal aging

Antero Salminen, Kai Kaarniranta

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 229 KB

english, 2011

7

ER stress and hormetic regulation of the aging process

Antero Salminen, Kai Kaarniranta

Journal:

Ageing Research Reviews

Year:

2010

Language:

english

File:

PDF, 655 KB

english, 2010

8

Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

Antero Salminen, Johanna Ojala, Kai Kaarniranta, Mikko Hiltunen, Hilkka Soininen

Journal:

Progress in Neurobiology

Year:

2011

Language:

english

File:

PDF, 306 KB

english, 2011

9

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

Kauppinen, Anu, Suuronen, Tiina, Ojala, Johanna, Kaarniranta, Kai, Salminen, Antero

Journal:

Cellular Signalling

Year:

2013

Language:

english

File:

PDF, 873 KB

english, 2013

10

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu, Ojala, Johanna, Haapasalo, Annakaisa, Soininen, Hilkka, Hiltunen, Mikko

Journal:

Progress in Neurobiology

Year:

2013

Language:

english

File:

PDF, 1.58 MB

english, 2013

11

AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions

Salminen, Antero, Kauppinen, Anu, Kaarniranta, Kai

Journal:

Cellular Signalling

Year:

2016

Language:

english

File:

PDF, 412 KB

english, 2016

12

The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process

Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu

Journal:

Ageing Research Reviews

Year:

2018

Language:

english

File:

PDF, 428 KB

english, 2018

13

SIRT1 longevity factor suppresses NF-κB -driven immune responses: regulation of aging via NF-κB acetylation?

Antero Salminen, Anu Kauppinen, Tiina Suuronen, Kai Kaarniranta

Journal:

Year:

2008

Language:

english

File:

PDF, 66 KB

english, 2008

14

Glycolysis links p53 function with NF-κB signaling: Impact on cancer and aging process

Antero Salminen, Kai Kaarniranta

Journal:

Journal of Cellular Physiology

Year:

2010

Language:

english

File:

PDF, 177 KB

english, 2010

15

Integration of a CIM tool management system to an intelligent feature-based process planning system

Seppo J. Torvinen, Kai Salminen, Lubomír Vasek

Journal:

Computers in Industry

Year:

1991

Language:

english

File:

PDF, 634 KB

english, 1991

16

The effect of 17β-estradiol on IL-6 secretion and NF-κB DNA-binding activity in human retinal pigment epithelial cells

Tuomas Paimela, Tuomas Ryhänen, Eliisa Mannermaa, Johanna Ojala, Giedrius Kalesnykas, Antero Salminen, Kai Kaarniranta

Journal:

Immunology Letters

Year:

2007

Language:

english

File:

PDF, 347 KB

english, 2007

17

Innate immunity meets with cellular stress at the IKK complex: Regulation of the IKK complex by HSP70 and HSP90

Antero Salminen, Tuomas Paimela, Tiina Suuronen, Kai Kaarniranta

Journal:

Immunology Letters

Year:

2008

Language:

english

File:

PDF, 332 KB

english, 2008

18

Apoptosis and aging: increased resistance to apoptosis enhances the aging process

Antero Salminen, Johanna Ojala, Kai Kaarniranta

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 315 KB

english, 2011

19

Siglec receptors and hiding plaques in Alzheimer's disease

Antero Salminen, Kai Kaarniranta

Journal:

Journal of Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 162 KB

english, 2009

20

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

Antero Salminen, Juha M. T. Hyttinen, Kai Kaarniranta

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 356 KB

english, 2011

21

In vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues: extraction studies

Anne Huhtala, Timo Pohjonen, Lotta Salminen, Antero Salminen, Kai Kaarniranta, Hannu Uusitalo

Journal:

Journal of Materials Science: Materials in Medicine

Year:

2008

Language:

english

File:

PDF, 216 KB

english, 2008

22

NF-κB Signaling in the Aging Process

Antero Salminen, Kai Kaarniranta

Journal:

Journal of Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 305 KB

english, 2009

23

Regulation of ERα Signaling Pathway in Neuronal HN10 Cells: Role of Protein Acetylation and Hsp90

Tiina Suuronen, Johanna Ojala, Juha M. T. Hyttinen, Kai Kaarniranta, Anders Thornell, Sergiy Kyrylenko, Antero Salminen

Journal:

Neurochemical Research

Year:

2008

Language:

english

File:

PDF, 359 KB

english, 2008

24

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

Antero Salminen, Johanna Ojala, Kai Kaarniranta, Annakaisa Haapasalo, Mikko Hiltunen, Hilkka Soininen

Journal:

European Journal of Neuroscience

Year:

2011

Language:

english

File:

PDF, 2.60 MB

english, 2011

25

AMP-activated protein kinase: a potential player in Alzheimer’s disease

Antero Salminen, Kai Kaarniranta, Annakaisa Haapasalo, Hilkka Soininen, Mikko Hiltunen

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 271 KB

english, 2011

26

SIRT1: Regulation of longevity via autophagy

Antero Salminen, Kai Kaarniranta

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 243 KB

english, 2009

27

Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling

Antero Salminen, Kai Kaarniranta

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 277 KB

english, 2010

28

Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells

Tuomas Ryhänen, Eliisa Mannermaa, Niku Oksala, Johanna Viiri, Tuomas Paimela, Antero Salminen, Mustafa Atalay, Kai Kaarniranta

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 720 KB

english, 2008

29

Influence of selective estrogen receptor modulators on interleukin-6 expression in human retinal pigment epithelial cells (ARPE-19)

Tuomas Paimela, Juha M.T. Hyttinen, Johanna Viiri, Tuomas Ryhänen, Matti K. Karvonen, Mikko Unkila, Hannu Uusitalo, Antero Salminen, Kai Kaarniranta

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 494 KB

english, 2010

30

NF-κB signaling as a putative target for ω-3 metabolites in the prevention of age-related macular degeneration (AMD)

Kai Kaarniranta, Antero Salminen

Journal:

Experimental Gerontology

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

31

Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

Antero Salminen, Johanna Ojala, Tiina Suuronen, Kai Kaarniranta, Anu Kauppinen

Journal:

Journal of Cellular and Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 1.72 MB

english, 2008

32

Regulatory role of HIF-1α in the pathogenesis of age-related macular degeneration (AMD)

Olli Arjamaa, Mikko Nikinmaa, Antero Salminen, Kai Kaarniranta

Journal:

Ageing Research Reviews

Year:

2009

Language:

english

File:

PDF, 357 KB

english, 2009

33

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

Antero Salminen, Jari Huuskonen, Johanna Ojala, Anu Kauppinen, Kai Kaarniranta, Tiina Suuronen

Journal:

Ageing Research Reviews

Year:

2008

Language:

english

File:

PDF, 553 KB

english, 2008

34

Heat shock proteins as gatekeepers of proteolytic pathways—Implications for age-related macular degeneration (AMD)

Kai Kaarniranta, Antero Salminen, Eeva-Liisa Eskelinen, Jürgen Kopitz

Journal:

Ageing Research Reviews

Year:

2009

Language:

english

File:

PDF, 746 KB

english, 2009

35

Genetics vs. entropy: Longevity factors suppress the NF-κB-driven entropic aging process

Antero Salminen, Kai Kaarniranta

Journal:

Ageing Research Reviews

Year:

2010

Language:

english

File:

PDF, 597 KB

english, 2010

36

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

Antero Salminen, Kai Kaarniranta

Journal:

Ageing Research Reviews

Year:

2012

Language:

english

File:

PDF, 811 KB

english, 2012

37

Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells

Tiina Suuronen, Tapio Nuutinen, Tuomas Ryhänen, Kai Kaarniranta, Antero Salminen

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 292 KB

english, 2007

38

ROCK, PAK, and Toll of synapses in Alzheimer’s disease

Antero Salminen, Tiina Suuronen, Kai Kaarniranta

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 194 KB

english, 2008

39

SIRT1 regulates the ribosomal DNA locus: Epigenetic candles twinkle longevity in the Christmas tree

Antero Salminen, Kai Kaarniranta

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 244 KB

english, 2009

40

Celastrol: Molecular targets of Thunder God Vine

Antero Salminen, Marko Lehtonen, Tuomas Paimela, Kai Kaarniranta

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 203 KB

english, 2010

41

Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells—Implications for age-related macular degeneration (AMD)

Anu Kauppinen, Henri Niskanen, Tiina Suuronen, Kati Kinnunen, Antero Salminen, Kai Kaarniranta

Journal:

Immunology Letters

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

42

Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells

Kai Kaarniranta, Tuomas Ryhänen, Reijo K. Sironen, Tiina Suuronen, Mika A. Elo, Hannu M. Karjalainen, Mikko J. Lammi, Markku Teräsvirta, Hannu Uusitalo, Antero Salminen

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 470 KB

english, 2005

43

Regulation of the aging process by autophagy

Antero Salminen, Kai Kaarniranta

Journal:

Trends in Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 296 KB

english, 2009

44

Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells

Kai Kaarniranta, Tuomas Ryhänen, Hannu M. Karjalainen, Mikko J. Lammi, Tiina Suuronen, Anne Huhtala, Matti Kontkanen, Markku Teräsvirta, Hannu Uusitalo, Antero Salminen

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 411 KB

english, 2005

45

Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population

Kai Kaarniranta, Jussi Paananen, Tanja Nevalainen, Iiris Sorri, Sanna Seitsonen, Ilkka Immonen, Antero Salminen, Leena Pulkkinen, Matti Uusitupa

Journal:

Neuroscience Letters

Year:

2012

Language:

english

File:

PDF, 283 KB

english, 2012

46

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

Antero Salminen, Johanna Ojala, Anu Kauppinen, Kai Kaarniranta, Tiina Suuronen

Journal:

Progress in Neurobiology

Year:

2009

Language:

english

File:

PDF, 531 KB

english, 2009

47

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

Antero Salminen, Kai Kaarniranta, Annakaisa Haapasalo, Mikko Hiltunen, Hilkka Soininen, Irina Alafuzoff

Journal:

Progress in Neurobiology

Year:

2012

Language:

english

File:

PDF, 505 KB

english, 2012

48

NEMO shuttle: A link between DNA damage and NF-κB activation in progeroid syndromes?

Antero Salminen, Tiina Suuronen, Jari Huuskonen, Kai Kaarniranta

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

49

ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

Antero Salminen, Anu Kauppinen, Tiina Suuronen, Kai Kaarniranta, Johanna Ojala

Journal:

Journal of Neuroinflammation

Year:

2009

Language:

english

File:

PDF, 434 KB

english, 2009

50

Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process

Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu

Journal:

Ageing Research Reviews

Year:

2013

Language:

english

File:

PDF, 748 KB

english, 2013